List
March 23rd, 2016

Enhanced oral paclitaxel bioavailability after administration of paclitaxel-loaded nanosponges

The aim of this study was to evaluate the pharmacokinetics of paclitaxel-loaded nanosponges (PLN) in rats. The study also evaluates […]
March 23rd, 2016

Cyclodextrin-based nanosponges encapsulating camptothecin: Physicochemical characterization, stability and cytotoxicity

Camptothecin (CAM), a plant alkaloid and a potent antitumor agent, has a limited therapeutic utility because of its poor aqueous […]
March 23rd, 2016

SMEDDS incorporated polymer matrix: A floating dosage form solution for drugs with poor gastric solubility

A new kind of gastro-retentlve dosage form for drugs with poor aqueous solubility was developed and evaluated, with the aim […]
March 23rd, 2016

In vitro release modulation and conformational stabilization of a model protein using swellable polyamidoamine nanosponges of β-cyclodextrin

New swellable cyclodextrin-based poly(amidoamine) nanosponges, named PAA-NS10 and PAA-NS11, were synthesized by crosslinking β-cyclodextrin with either 2,2-bisacrylamidoacetic acid or with […]
March 23rd, 2016

Nanosponge formulations as oxygen delivery systems

Three types of cyclodextrin nanosponges were synthetized cross-linking α, β or γ cyclodextrin with carbonyldiimidazole as cross-linker. Nanosponges are solid […]
March 23rd, 2016

Evaluation of synthesized cross linked polyvinyl alcohol as potential disintegrant

Purpose: The present study deals with evaluation of crosslinked poly vinyl alcohol (PVA) as a potential disintegrant. Methods: Crosslinking of […]