List
March 23rd, 2016

Novel bilayer dissolving microneedle arrays with concentrated PLGA nano-microparticles for targeted intradermal delivery: Proof of concept

Polymeric microneedle (MN) arrays continue to receive growing attention due to their ability to bypass the skin’s stratum corneum barrier in a […]

March 23rd, 2016

Nose to Brain Delivery of Rivastigmine by In Situ Gelling Cationic Nanostructured Lipid Carriers: Enhanced Brain Distribution and Pharmacodynamics

Present investigation explores the potential of nanostructured lipid carriers (NLCs) for nose to brain delivery of rivastigmine (RV), which is […]

March 23rd, 2016

Zero order controlled release delivery of cholecalciferol from injectable biodegradable microsphere: In-vitro characterization and in-vivo pharmacokinetic studies

Poly(lactic-co-glycolic acid) microspheres loaded with cholecalciferol (CL), more bioactive form of vitamin D was developed as an injectable controlled drug releasesystem and was evaluated for its feasibility […]

March 23rd, 2016

Development and characterization of an organic solvent free, proliposomal formulation of Busulfan using quality by design approach

Parenteral administration of Busulfan (BU) conquers the bioavailability and biovariability related issues of oral BU by maintaining the plasma drug concentrationin therapeutic range with minimal fluctuations […]

March 23rd, 2016

Rational Design of Cholesterol Derivative for Improved Stability of Paclitaxel Cationic Liposomes

Purpose This work explores synthesis of novel cholesterol derivative for the preparation of cationic liposomes and its interaction with Paclitaxel […]

March 23rd, 2016

Cationic cholesterol derivative efficiently delivers the genes: in silico and in vitro studies

The aims of the research work were to synthesize ethyl(cholesteryl carbamoyl)-l-arginate (ECCA), an arginine-conjugated cholesterol derivative, and to evaluate its […]