List
March 23rd, 2016

Physicochemical, in silico and in vivo evaluation of a danazol-β-cyclodextrin complex

Inclusion complexation of danazol with β-cyclodextrin (BCD) in aqueous solution, in solid state and in silico state was investigated to […]
March 23rd, 2016

Preparation and evaluation of taste masked famotidine formulation using drug/β-cyclodextrin/polymer ternary complexation approach

The main aim of the present study was to evaluate potential of ternary complexation (comprising of drug, cyclodextrin and polymer) […]
March 23rd, 2016

Bioadhesive ranitidine hydrochloride for gastroretention with controlled microenvironmental pH

Ranitidine hydrochloride is a H2 receptor blocker used in the treatment of gastric ulcers. Pharmacological factors, in addition to the […]
March 23rd, 2016

Gamma irradiated micro system for long-term parenteral contraception: An alternative to synthetic polymers

An injectable system of levonorgestrel (LNG) was developed using biodegradable polymer of natural origin. The parenteral system was optimized for […]
March 23rd, 2016

Electron beam irradiation: A novel technology for the development of transdermal system of isosorbide dinitrate

The development of a transdermal delivery system for isosorbide dinitrate (ISDN) using electron beam irradiation was studied. The solid state […]
March 23rd, 2016

Evaluation of alkyl polyglucoside as an alternative surfactant in the preparation of peptide-loaded nanoparticles

The present study was carried out to evaluate potentials of alkyl polyglucoside (APG) as an alternative surfactant/stabilizer in the preparation […]
March 23rd, 2016

The influence of absorption enhancers on nasal absorption of acyclovir

The objective of this work was to increase the nasal absorption of acyclovir by using absorption enhancers. Acyclovir was selected […]
March 23rd, 2016

Fabrication, characterization and in vivo studies of biodegradable gamma sterilized injectable microparticles for contraceptionVavia

A Levonorgestrel-loaded microparticulate system was developed with gelatin and bovine serum albumin using triple emulsion technique coupled with chemical cross-linking […]
March 23rd, 2016

Nasal drug delivery of sumatriptan succinate

The purpose of this work was to increase the nasal absorption of sumatriptan succinate by using bile salts. A rat […]
March 23rd, 2016

Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application

Polymeric nanoparticle suspensions (NS) were prepared from poly(lactide-co-glycolide) and poly(lactide-co-glycolide-leucine) {poly[Lac(Glc-Leu)]} biodegradable polymers and loaded with diclofenac sodium (DS), with […]