List
March 23rd, 2016

Fabrication, characterization and in vivo studies of biodegradable gamma sterilized injectable microparticles for contraceptionVavia

A Levonorgestrel-loaded microparticulate system was developed with gelatin and bovine serum albumin using triple emulsion technique coupled with chemical cross-linking […]
March 23rd, 2016

Nasal drug delivery of sumatriptan succinate

The purpose of this work was to increase the nasal absorption of sumatriptan succinate by using bile salts. A rat […]
March 23rd, 2016

Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application

Polymeric nanoparticle suspensions (NS) were prepared from poly(lactide-co-glycolide) and poly(lactide-co-glycolide-leucine) {poly[Lac(Glc-Leu)]} biodegradable polymers and loaded with diclofenac sodium (DS), with […]
March 23rd, 2016

Development of sustained release gastroretentive drug delivery system for ofloxacin: In vitro and in vivo evaluation

Sustained release (SR)-gastroretentive dosage forms (GRDF) enable prolonged and continuous input of the drug to the upper parts of the […]
March 23rd, 2016

Formulation and performance characterization of radio-sterilized "Progestin-only" microparticles intended for contraception

The aim of this study was to formulate and characterize a microparticulate system of progestin-only contraceptive. Another objective was to […]
March 23rd, 2016

Novel sustained release, swellable and bioadhesive gastroretentive drug delivery system for ofloxacin

Oral sustained release gastroretentive dosage forms offer many advantages for drugs having absorption from upper gastrointestinal tract and improve the […]
March 23rd, 2016

Effect of hydrophilic polymer on solubilization of fenofibrate by cyclodextrin complexation

The present work investigates the possibility of improvement of the complexation efficiency of cyclodextrin towards a drug by adding a […]
March 23rd, 2016

Drug loaded poly[Lac(Glc-Leu)] microparticles: Formulation and release characteristics

Valdecoxib has been entrapped in sub-5 μm particles of poly[Lac(Glc-Leu)] copolymer using a oil-in-water (o/w) emulsification-solvent evaporation technique. To achieve […]
March 23rd, 2016

Complexation approach for fixed dose tablet formulation of lopinavir and ritonavir: An anomalous relationship between stability constant, dissolution rate and saturation solubility

In the present investigation, cyclodextrin complexation process was explored for development of tablet formulation of WHO approved fixed dose combination […]
March 23rd, 2016

Pharmacokinetics of intramuscular microparticle depot of valdecoxib in an experimental model Pharmacokinetics of intramuscular microparticle depot

Aim: We did a prospective study to investigate pharmacokinetics of a single intramuscularly (i.m.) administered Valdecoxib (VC) polymeric microparticles in […]