List
March 23rd, 2016

Development of sustained release gastroretentive drug delivery system for ofloxacin: In vitro and in vivo evaluation

Sustained release (SR)-gastroretentive dosage forms (GRDF) enable prolonged and continuous input of the drug to the upper parts of the […]
March 23rd, 2016

Formulation and performance characterization of radio-sterilized "Progestin-only" microparticles intended for contraception

The aim of this study was to formulate and characterize a microparticulate system of progestin-only contraceptive. Another objective was to […]
March 23rd, 2016

Novel sustained release, swellable and bioadhesive gastroretentive drug delivery system for ofloxacin

Oral sustained release gastroretentive dosage forms offer many advantages for drugs having absorption from upper gastrointestinal tract and improve the […]
March 23rd, 2016

Effect of hydrophilic polymer on solubilization of fenofibrate by cyclodextrin complexation

The present work investigates the possibility of improvement of the complexation efficiency of cyclodextrin towards a drug by adding a […]
March 23rd, 2016

Inclusion complexation of Anti-HIV drug with β-cyclodextrin

The purpose of present investigation was to investigate the effect of complexation of Nelfinavir Mesylate (NM) – an Anti-HIV drug […]
March 23rd, 2016

Interaction of valdecoxib with β-cyclodextrin: Experimental and molecular modeling studies

This study aimed to investigate the effect of β-cyclodextrin on aqueous solubility and dissolution rate of valdecoxib and also to […]
March 23rd, 2016

Formulation of betacyclodextrin based nanosponges of itraconazole

Nanosponges are betacyclodextrins crosslinked with carbonate bonds. The polymer formed is nanoparticulate in nature. Itraconazole is a BCS Class II […]
March 23rd, 2016

Cyclodextrin-based nanosponges encapsulating camptothecin: Physicochemical characterization, stability and cytotoxicity

Camptothecin (CAM), a plant alkaloid and a potent antitumor agent, has a limited therapeutic utility because of its poor aqueous […]
March 23rd, 2016

SMEDDS incorporated polymer matrix: A floating dosage form solution for drugs with poor gastric solubility

A new kind of gastro-retentlve dosage form for drugs with poor aqueous solubility was developed and evaluated, with the aim […]
March 23rd, 2016

In vitro release modulation and conformational stabilization of a model protein using swellable polyamidoamine nanosponges of β-cyclodextrin

New swellable cyclodextrin-based poly(amidoamine) nanosponges, named PAA-NS10 and PAA-NS11, were synthesized by crosslinking β-cyclodextrin with either 2,2-bisacrylamidoacetic acid or with […]