List
March 23rd, 2016

Evaluation of synthesized cross linked polyvinyl alcohol as potential disintegrant

Purpose: The present study deals with evaluation of crosslinked poly vinyl alcohol (PVA) as a potential disintegrant. Methods: Crosslinking of […]
March 23rd, 2016

Paclitaxel loaded nanosponges: In-vitro characterization and cytotoxicity study on MCF-7 cell line culture

Beta cyclodextrin (β-CD) based nanosponges were synthesized and paclitaxel inclusion complex with nano-sponges were prepared using techniques of inclusion complex […]
March 23rd, 2016

Cyclodextrin-based nanosponges for delivery of resveratrol: In vitro characterisation, stability, cytotoxicity and permeation study

The aim of this work was to increase the solubility, stability and permeation of resveratrol by complexation with cyclodextrin-based nanosponges […]
March 23rd, 2016

Synthesis and characterization of amphiphilic star copolymer of beta-cyclodextrin and polypropylene oxide and their application as nanocarriers

The present study was aimed at synthesizing and characterizing star copolymers of β-cyclodextrin and exploring their application as nanocarriers. The […]
March 23rd, 2016

Inclusion complexation of weakly acidic NSAID with β-cyclodextrin: Selection of arginine, an amino acid, as a novel ternary component

The purpose of the present study was to investigate the influence of an amino acid, arginine, as a ternary component […]
March 23rd, 2016

Effect of decisive formulation variables on bioencapsulation efficiency and integrity of yeast biocapsules for oral itraconazole delivery

Reproducible delivery of drugs through bioencapsulation in cellular carriers is severely limited by biovariability in cellular carriers and effects of […]
March 23rd, 2016

Cyclodextrin nanosponges as effective gas carriers

Cyclodextrin based carbonate nanosponges were synthetized starting from native β-cylodextrin and active carbonyl compounds i.e. carbonildiimidazole. In this work they […]
March 23rd, 2016

Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution

Background: Lumefantrine, an antimalarial molecule has very low and variable bioavailability owing to its extremely poor solubility in water. It […]
March 23rd, 2016

Structural evidence of differential forms of nanosponges of beta-cyclodextrin and its effect on solubilization of a model drug

Nanosponges (NS) are a recently developed class of hyper-branched polymers, nano-structured to form three dimensional meshwork; obtained by reacting cyclodextrins […]
March 23rd, 2016

Nanosponges encapsulating dexamethasone for ocular delivery: Formulation design, physicochemical characterization, safety and corneal permeability assessment

Nanosponges (NS) were synthesized by crosslinking of beta cyclodextrins with diphenyl carbonate. It is a hyper-branched polymer with an ultra […]