List
March 23rd, 2016

Design, synthesis and evaluation of N-acetyl glucosamine (NAG)-PEG-doxorubicin targeted conjugates for anticancer delivery

Efficacy of anticancer drug is limited by the severe adverse effects induced by drug; therefore the crux is in designing […]
March 23rd, 2016

Rivastigmine-loaded L-lactide-depsipeptide polymeric nanoparticles: Decisive formulation variable optimization

The main aim of the investigation was to explore a novel L-lactide-depsipeptide copolymer for the development of rivastigmine-loaded polymeric nanoparticles. […]
March 23rd, 2016

Felodipine b-cyclodextrin complex as an active core for time delayed chronotherapeutic treatment of hypertension

The present research work deals with the development of a time delayed chronotherapeutic formulation of felodipine (FD) aimed at rapid […]
March 23rd, 2016

Preparation and characterization of solid lipid nanoparticle-based nasal spray of budesonide

The present research work was aimed at developing solid lipid nanoparticle (SLN)-based formulation of budesonide (BDS) for nasal delivery. Melt […]
March 23rd, 2016

Nanolipidgel for enhanced skin deposition and improved antifungal activity

The purpose of the research was to prepare and evaluate a topical nanolipidgel (NLH) of terbinafine hydrochloride (TRB), an antimycotic […]
March 23rd, 2016

Fabrication of isradipine nanosuspension by anti-solvent microprecipitation-high-pressure homogenization method for enhancing dissolution rate and oral bioavailability

The aim of this study was to develop a nanosuspension of a highly hydrophobic drug, isradipine (ISR) by combination of […]
March 23rd, 2016

Amorphous ternary cyclodextrin nanocomposites of telmisartan for oral drug delivery: Improved solubility and reduced pharmacokinetic variability

Despite of advancements in dosage form design and use of multifunctional excipients, improvement in dissolution characteristics of molecules like Telmisartan […]
March 23rd, 2016

Cyclodextrin-based nanosponges of curcumin: Formulation and physicochemical characterization

Curcumin is the source of the spice turmeric having potential application in tumor treatment but has limited therapeutic utility because […]
March 23rd, 2016

Nanosuspension based in situ gelling nasal spray of carvedilol: Development, in vitro and in vivo characterization

The objective of the present investigation was to develop in situ gelling nasal spray formulation of carvedilol (CRV) nanosuspension to […]
March 23rd, 2016

Soluble itraconazole in tablet form using disordered drug delivery approach: Critical scale-up considerations and bio-equivalence studies

The present research work explores formulation design, critical scale-up considerations and bio-equivalence studies of soluble itraconazole (ITZ) in a tablet […]