A single dose complete cross over study of enalapril maleate (10 mg tablet) conventional formulations marketed in India was carried in 8 healthy male volunteers. The formulations were compared with a standard formulation of enalapril maleate 10 mg tablet. Analysis of plasma was done by using an indirect method of angiotensin I radioimmunoassay (RIA) method. Pharmacokinetic parameters such as Cmax, Tmax, Kel, AUC0-24 and T( 1/2 ) were determined and subjected to statistical analysis. In vitro dissolution studies on high performance liquid chromatography (HPLC) of the formulation included in the study was also carried out.

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