List
March 23rd, 2016

Polymeric nanoparticle formulation of octapeptide (NP-OP): In vitro release and in vivo effect in common marmosets, Callithrix jacchus Linn

Octapeptide (OP)/FSH-Receptor Binding Inhibitor-8 (FRBI-8), is a synthetic peptide corresponding to N-terminal sequence of purified fraction of Follicle Stimulating Hormone […]
March 23rd, 2016

Structural evidence of differential forms of nanosponges of beta-cyclodextrin and its effect on solubilization of a model drug

Nanosponges (NS) are a recently developed class of hyper-branched polymers, nano-structured to form three dimensional meshwork; obtained by reacting cyclodextrins […]
March 23rd, 2016

Nanosponges encapsulating dexamethasone for ocular delivery: Formulation design, physicochemical characterization, safety and corneal permeability assessment

Nanosponges (NS) were synthesized by crosslinking of beta cyclodextrins with diphenyl carbonate. It is a hyper-branched polymer with an ultra […]
March 23rd, 2016

Physico-chemical characterization and in vivo pharmacodynamic evaluation of lyophilized meloxicam: β-cyclodextrin inclusion complexes

Objective: The objective of the present work was to enhance solubility, in vitro dissolution and in vivo pharmacodynamic activity of […]
March 23rd, 2016

Niosomal gel of lornoxicam for topical delivery: In vitro assessment and pharmacodynamic activity

Lornoxicam is a potent oxicam class of non steroidal anti-inflammatory agent, prescribed for mild to moderate pain and inflammation. Niosomal […]
March 23rd, 2016

Rivastigmine-loaded L-lactide-depsipeptide polymeric nanoparticles: Decisive formulation variable optimization

The main aim of the investigation was to explore a novel L-lactide-depsipeptide copolymer for the development of rivastigmine-loaded polymeric nanoparticles. […]
March 23rd, 2016

Preparation and characterization of solid lipid nanoparticle-based nasal spray of budesonide

The present research work was aimed at developing solid lipid nanoparticle (SLN)-based formulation of budesonide (BDS) for nasal delivery. Melt […]
March 23rd, 2016

Nanolipidgel for enhanced skin deposition and improved antifungal activity

The purpose of the research was to prepare and evaluate a topical nanolipidgel (NLH) of terbinafine hydrochloride (TRB), an antimycotic […]
March 23rd, 2016

Fabrication of isradipine nanosuspension by anti-solvent microprecipitation-high-pressure homogenization method for enhancing dissolution rate and oral bioavailability

The aim of this study was to develop a nanosuspension of a highly hydrophobic drug, isradipine (ISR) by combination of […]
March 23rd, 2016

Amorphous ternary cyclodextrin nanocomposites of telmisartan for oral drug delivery: Improved solubility and reduced pharmacokinetic variability

Despite of advancements in dosage form design and use of multifunctional excipients, improvement in dissolution characteristics of molecules like Telmisartan […]