List
March 23rd, 2016

Poly[LA-(Glc-Leu)] copolymer as a carrier for ocular delivery of ciprofloxacin: Formulation, characterization and in vivo biocompatibility study

Background: Ciprofloxacin hydrochloride-encapsulated poly[LA-(Glc-Leu)] copolymeric nanoparticles were prepared to provide sustained release and ameliorate shortcomings associated with eye drops. Methods: […]

March 23rd, 2016

Cyclodextrin-based nanosponges: effective nanocarrier for tamoxifen delivery.

The purpose of the present study was to develop Tamoxifen loaded β-cyclodextrin nanosponges for oral drug delivery. The three types […]

March 23rd, 2016

Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution

Background: Lumefantrine, an antimalarial molecule has very low and variable bioavailability owing to its extremely poor solubility in water. It […]

March 23rd, 2016

Structural evidence of differential forms of nanosponges of beta-cyclodextrin and its effect on solubilization of a model drug

Nanosponges (NS) are a recently developed class of hyper-branched polymers, nano-structured to form three dimensional meshwork; obtained by reacting cyclodextrins […]

March 23rd, 2016

Nanosponges encapsulating dexamethasone for ocular delivery: Formulation design, physicochemical characterization, safety and corneal permeability assessment

Nanosponges (NS) were synthesized by crosslinking of beta cyclodextrins with diphenyl carbonate. It is a hyper-branched polymer with an ultra […]

March 23rd, 2016

Physico-chemical characterization and in vivo pharmacodynamic evaluation of lyophilized meloxicam: β-cyclodextrin inclusion complexes

Objective: The objective of the present work was to enhance solubility, in vitro dissolution and in vivo pharmacodynamic activity of […]

March 23rd, 2016

Niosomal gel of lornoxicam for topical delivery: In vitro assessment and pharmacodynamic activity

Lornoxicam is a potent oxicam class of non steroidal anti-inflammatory agent, prescribed for mild to moderate pain and inflammation. Niosomal […]

March 23rd, 2016

Rivastigmine-loaded L-lactide-depsipeptide polymeric nanoparticles: Decisive formulation variable optimization

The main aim of the investigation was to explore a novel L-lactide-depsipeptide copolymer for the development of rivastigmine-loaded polymeric nanoparticles. […]

March 23rd, 2016

Development, characterisation and evaluation of supersaturated triglyceride free drug delivery (s-TFDDS) of lornoxicam

The present work was aimed at formulating a supersaturated triglyceride free drug delivery system (s-TFDDS) of lornoxicam and evaluating its […]

March 23rd, 2016

Effect of permeation enhancers on dynamic mechanical properties of acrylate pressure sensitive adhesives

Physico-chemical properties of permeation enhancers like molecular weight/size, hydrophobicity/hydrophilicity, co-solvency, etc. are necessary during their selection for pharmaceutical product development. […]