List
March 23rd, 2016

Novel L-lactide-depsipeptide polymeric carrier for enhanced brain uptake of rivastigmine in treatment of alzheimer’s disease

The present study discusses possibility of targeting an anti-Alzheimer’s drug rivastigmine tartarate (RT) to the brain using novel synthesized L-lactide-depsipeptide […]

March 23rd, 2016

Electron capture detection of oxybutynin in plasma: Precolumn derivatization approach and application to a pharmacokinetic study

Oxybutynin is an antimuscarinic agent used for the treatment of an overactive bladder. Because of its poor chromophore, it is […]

March 23rd, 2016

Serratiopeptidase Loaded Chitosan Nanoparticles by Polyelectrolyte Complexation: In Vitro and In Vivo Evaluation

The aim of the present study was to formulate serratiopeptidase (SER)-loaded chitosan (CS) nanoparticles for oral delivery. SER is a […]

March 23rd, 2016

Oral delivery of paclitaxel nanocrystal (PNC) with a dual Pgp-CYP3A4 inhibitor: Preparation, characterization and antitumor activity

Several molecular inheritances have severely restrained the peroral delivery of taxanes. The main objective of the present investigation was to […]

March 23rd, 2016

Rivastigmine-loaded in situ gelling nanostructured lipid carriers for nose to brain delivery

In the current research work, rivastigmine (RV)-loaded in situ gelling nanostructured lipid carriers (NLCs) were developed for nose to brain […]

March 23rd, 2016

Development, characterisation and evaluation of supersaturated triglyceride free drug delivery (s-TFDDS) of lornoxicam

The present work was aimed at formulating a supersaturated triglyceride free drug delivery system (s-TFDDS) of lornoxicam and evaluating its […]

March 23rd, 2016

Efficacy Interactions of PEG-DOX-N-acetyl Glucosamine Prodrug Conjugate for Anticancer Therapy

Present investigation is exploring structure-biocompatibility interaction of tumour targeted polyethylene glycol (PEG) based drug conjugate of doxorubicin using N-acetyl glucosamine […]

March 23rd, 2016

Effect of permeation enhancers on dynamic mechanical properties of acrylate pressure sensitive adhesives

Physico-chemical properties of permeation enhancers like molecular weight/size, hydrophobicity/hydrophilicity, co-solvency, etc. are necessary during their selection for pharmaceutical product development. […]

March 23rd, 2016

Glucosamine anchored cancer targeted nano-vesicular drug delivery system of doxorubicin

Background: Efficacy of an anticancer drug is challenged by severe adverse effects persuaded by the drug itself; hence designing a […]

March 23rd, 2016

Medium chain triglyceride (MCT) rich, paclitaxel loaded self nanoemulsifying preconcentrate (PSNP): A safe and efficacious alternative to taxol®

The current work was aimed to develop Medium Chain Triglyceride (MCT) rich self nanoemulsifying preconcentrate of paclitaxel (PTX) for parenteral […]