List
March 23rd, 2016

Cyclodextrin-based nanosponges: effective nanocarrier for tamoxifen delivery.

The purpose of the present study was to develop Tamoxifen loaded β-cyclodextrin nanosponges for oral drug delivery. The three types […]
March 23rd, 2016

Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution

Background: Lumefantrine, an antimalarial molecule has very low and variable bioavailability owing to its extremely poor solubility in water. It […]
March 23rd, 2016

Structural evidence of differential forms of nanosponges of beta-cyclodextrin and its effect on solubilization of a model drug

Nanosponges (NS) are a recently developed class of hyper-branched polymers, nano-structured to form three dimensional meshwork; obtained by reacting cyclodextrins […]
March 23rd, 2016

Nanosponges encapsulating dexamethasone for ocular delivery: Formulation design, physicochemical characterization, safety and corneal permeability assessment

Nanosponges (NS) were synthesized by crosslinking of beta cyclodextrins with diphenyl carbonate. It is a hyper-branched polymer with an ultra […]
March 23rd, 2016

Physico-chemical characterization and in vivo pharmacodynamic evaluation of lyophilized meloxicam: β-cyclodextrin inclusion complexes

Objective: The objective of the present work was to enhance solubility, in vitro dissolution and in vivo pharmacodynamic activity of […]
March 23rd, 2016

Technology improves bioavailability of some drugs, offers formulation versatility and holds potential for a revolution in nano therapies

[No abstract available]
March 23rd, 2016

Niosomal gel of lornoxicam for topical delivery: In vitro assessment and pharmacodynamic activity

Lornoxicam is a potent oxicam class of non steroidal anti-inflammatory agent, prescribed for mild to moderate pain and inflammation. Niosomal […]
March 23rd, 2016

Serratiopeptidase Loaded Chitosan Nanoparticles by Polyelectrolyte Complexation: In Vitro and In Vivo Evaluation

The aim of the present study was to formulate serratiopeptidase (SER)-loaded chitosan (CS) nanoparticles for oral delivery. SER is a […]
March 23rd, 2016

Oral delivery of paclitaxel nanocrystal (PNC) with a dual Pgp-CYP3A4 inhibitor: Preparation, characterization and antitumor activity

Several molecular inheritances have severely restrained the peroral delivery of taxanes. The main objective of the present investigation was to […]
March 23rd, 2016

Rivastigmine-loaded in situ gelling nanostructured lipid carriers for nose to brain delivery

In the current research work, rivastigmine (RV)-loaded in situ gelling nanostructured lipid carriers (NLCs) were developed for nose to brain […]